Lenalidomide-Br ( —— )

Catalog No. M23940 CAS No. 2093387-36-9

Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Lenalidomide-Br
Note

Research use only, not for human use.
Brief Description

Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.
Description

Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC STAT3 degrader SD-36[1][2].
Synonyms

——
Pathway

PROTACs
Target

PROTAC
Recptor

Cereblon
Research Area

——
Indication

——

Chemical Information

CAS Number

2093387-36-9
Formula Weight

323.1
Molecular Formula

C13H11BrN2O3
Purity

>98% (HPLC)
Solubility

DMSO : 30 mg/mL (92.84 mM; Need ultrasonic)
SMILES

O=C(C(N(CC1=C2C=CC=C1Br)C2=O)CC3)NC3=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.

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