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Lenalidomide-Br

CAS No. 2093387-36-9

Lenalidomide-Br( —— )

Catalog No. M23940 CAS No. 2093387-36-9

Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Lenalidomide-Br
  • Note
    Research use only, not for human use.
  • Brief Description
    Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.
  • Description
    Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC STAT3 degrader SD-36.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    Cereblon
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2093387-36-9
  • Formula Weight
    323.14
  • Molecular Formula
    C13H11BrN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 30 mg/mL (92.84 mM; Need ultrasonic)
  • SMILES
    O=C(C(N(CC1=C2C=CC=C1Br)C2=O)CC3)NC3=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.
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