Lenacapavir

CAS No. 2189684-44-2

Lenacapavir ( GS-6207 )

Catalog No. M26233 CAS No. 2189684-44-2

Lenacapavir is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 621 Get Quote
10MG 1017 Get Quote
25MG 1503 Get Quote
50MG 2025 Get Quote
100MG 2673 Get Quote
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Biological Information

  • Product Name
    Lenacapavir
  • Note
    Research use only, not for human use.
  • Brief Description
    Lenacapavir is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
  • Description
    Lenacapavir is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.(In Vitro):Lenacapavir displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells. Lenacapavir shows sub-nanomolar potency in target cells with EC50 of 23 pM, in a full-cycle assay with EC50 of 25 pM and in producer cells with EC50 of 439 pM.
  • Synonyms
    GS-6207
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2189684-44-2
  • Formula Weight
    968.3
  • Molecular Formula
    C39H32ClF10N7O5S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@]12C[C@@]1([H])C(F)(F)c1c2c(nn1CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(ccc1-c1ccc(Cl)c2c(NS(C)(=O)=O)nn(CC(F)(F)F)c12)C#CC(C)(C)S(C)(=O)=O)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tagliabue A, Rappuoli R. Vaccine adjuvants:the dream becomes real. Hum Vaccin. 2008 Sep-Oct;4(5):347-9.
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