Latrepirdine ( Latrepirdine dimebolin Dimebon )

Catalog No. M17697 CAS No. 97657-92-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

Latrepirdine
Note

Research use only, not for human use.
Brief Description

Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.
Description

Latrepirdine, also known as dimebolin (sold as Dimebon), is an antihistamine drug which has been used clinically in Russia since 1983. Research is continuing in both Russia and western nations into potential applications as a neuroprotective drug to combat Alzheimer's disease and, possibly, as a nootropic as well. However, a Phase III clinical trial for Alzheimer's disease treatment failed to show any benefit.
Synonyms

Latrepirdine dimebolin Dimebon
Pathway

Others
Target

Other Targets
Recptor

GluR , Histamine receptor , 5-HT
Research Area

Inflammation/Immunology
Indication

——

CAS Number

97657-92-6
Formula Weight

392.37
Molecular Formula

C21H25N3·2HCl
Purity

98%
Solubility

DMSO : 6.4 mg/mL. 16.31 mM;
SMILES

CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl
Chemical Name

2,8-dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride

1. Zhang S, et al. J Alzheimers Dis, 2010, 21(2), 389-402.

Calculator

molnova catalog