Latrepirdine

Research use only, not for human use.

Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.

Latrepirdine, also known as dimebolin (sold as Dimebon), is an antihistamine drug which has been used clinically in Russia since 1983. Research is continuing in both Russia and western nations into potential applications as a neuroprotective drug to combat Alzheimer's disease and, possibly, as a nootropic as well. However, a Phase III clinical trial for Alzheimer's disease treatment failed to show any benefit.

Latrepirdine dimebolin Dimebon

Others

Other Targets

GluR , Histamine receptor , 5-HT

Inflammation/Immunology

——

97657-92-6

392.37

C21H25N3·2HCl

98%

DMSO : 6.4 mg/mL. 16.31 mM;

CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl

2,8-dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride

(-20℃)

With Ice Pack

≥ 2 years