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Labetuzumab

CAS No. 219649-07-7

Labetuzumab( —— )

Catalog No. M37694 CAS No. 219649-07-7

Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with anticancer activity that inhibits tumor growth and is used in the study of thyroid and colorectal cancer (CRC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 527 Get Quote
5MG 660 Get Quote
10MG 1036 Get Quote
25MG 1527 Get Quote
50MG 2052 Get Quote
100MG 2655 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    Labetuzumab
  • Note
    Research use only, not for human use.
  • Brief Description
    Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with anticancer activity that inhibits tumor growth and is used in the study of thyroid and colorectal cancer (CRC).
  • Description
    Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy.
  • In Vitro
    ——
  • In Vivo
    Labetuzumab (0.5 mg/rat; i.v.; single) inhibits tumor growth in vivo.Animal Model:Female nu/nu mice (6 to 8-week-old; inject TT cells).Dosage:0.5 mg/rat Administration:Intravenous injection; single (1 day post-tumor cell injection) Result:Significantly delaied growth of tumor, and led to 64%-70% inhibition of tumor size between days 32 and 60.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    219649-07-7
  • Formula Weight
    145.1 kDa
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Stein R, et al. A humanized monoclonal antibody to carcinoembryonic antigen, labetuzumab, inhibits tumor growth and sensitizes human medullary thyroid cancer xenografts to dacarbazine chemotherapy. Mol Cancer Ther. 2004 Dec;3(12):1559-64. ?
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