YAP/TAZ inhibitor-1( —— )

Catalog No. M33175 CAS No. 2093565-23-0

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Datasheet

HNMR

HPLC

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Product Name

YAP/TAZ inhibitor-1
Note

Research use only, not for human use.
Brief Description

YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor (IC50 <0.100 μΜ) for the study of abnormal immune function and cancer.
Description

YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0.100 μΜ in firefly luciferase assay.
In Vitro

YAP and TAZ are transcriptional co-activators of the Hippo pathway network and regulate cell proliferation, migration, and apoptosis. YAP/TAZ inhibitor-1 is an inhibitor of transcriptional coactivator with PDZ binding motif/Yes- associated protein transcriptional coactivator (TAZ/YAP).
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

YAP
Research Area

——
Indication

——

CAS Number

2093565-23-0
Formula Weight

621.81
Molecular Formula

C33H39N3O5S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (100.51 mM; Ultrasonic )
SMILES

CC(N1CCN(CC1)S(=O)(=O)c1ccc2-c3ccc(cc3\C(=N/O)c2c1)S(=O)(=O)C1CCC(C)(C)CC1)c1ccccc1
Chemical Name

——

1. Tracy Tzu-Ling Tang Lin, et al. Tricyclic compounds. WO2017058716A1.

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