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LYS228
CAS No. 1810051-96-7
LYS228( LYS-228 | LYS 228 )
Catalog No. M12777 CAS No. 1810051-96-7
LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameLYS228
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NoteResearch use only, not for human use.
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Brief DescriptionLYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml.
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DescriptionLYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml; LYS228 is stable against Metallo-β-lactamases (MBLs), and shows small or no MIC shifts for most SBLs (serine β-lactamases), including CTX-Ms, KPCs and OXA-types.Bacterial Infection Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsLYS-228 | LYS 228
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaInfection
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IndicationBacterial Infection
Chemical Information
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CAS Number1810051-96-7
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Formula Weight518.472
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Molecular FormulaC16H18N6O10S2
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Purity>98% (HPLC)
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Solubility——
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SMILESC1CC1(C(=O)O)ON=C(C2=CSC(=N2)N)C(=O)NC3C(N(C3=O)S(=O)(=O)O)CN4CCOC4=O
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Chemical Name1-((((Z)-1-(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3-yl)amino)ethylidene)amino)oxy)cyclopropane-1-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Reck F, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755.
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