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LY379196
CAS No. 737736-10-6
LY379196( LY 379196 )
Catalog No. M15820 CAS No. 737736-10-6
LY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameLY379196
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NoteResearch use only, not for human use.
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Brief DescriptionLY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII.
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DescriptionLY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII, displays >10-fold selectivity of PKCα, δ, η, and γ (>600 nM); blocks TPA-induced monocytic differentiation of HL60 cells.
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In Vitro——
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In Vivo——
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SynonymsLY 379196
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research Area——
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Indication——
Chemical Information
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CAS Number737736-10-6
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Formula Weight——
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Molecular FormulaC29H30N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(12E,32E,6S)-6-((dimethylamino)methyl)-22,25-dihydro-11H,21H,31H-1,3(3,1)-diindola-2(3,4)-pyrrolacyclononaphane-22,25-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jirousek MR, et al. J Med Chem. 1996 Jul 5;39(14):2664-71.
2. Slosberg ED, et al. Mol Carcinog. 2000 Mar;27(3):166-76.
3. Tabit CE, et al. Circulation. 2013 Jan 1;127(1):86-95.
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