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PKCiota-IN-2
CAS No. 2230055-52-2
PKCiota-IN-2( —— )
Catalog No. M37688 CAS No. 2230055-52-2
PKCiota-IN-2 (PKCiota-IN-49) is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 279 | In Stock |
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| 2MG | 166 | In Stock |
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| 5MG | 256 | In Stock |
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| 10MG | 375 | In Stock |
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| 25MG | 562 | In Stock |
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| 50MG | 776 | In Stock |
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| 100MG | 1042 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePKCiota-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionPKCiota-IN-2 (PKCiota-IN-49) is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively
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DescriptionPKCiota-IN-2 is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research Area——
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Indication——
Chemical Information
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CAS Number2230055-52-2
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Formula Weight395.46
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Molecular FormulaC24H21N5O
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C)C1=C(C2=C3N(N=C2)C=CC(=C3)C4=C5C(=NC=C4)NC=C5)C=C6C(=C1)CCNC6
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jacek Kwiatkowski, et al. Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors. J Med Chem. 2018 May 24;61(10):4386-4396. ?
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