LY305

CAS No. 1430230-83-3

LY305( LY 305 | LY-305 )

Catalog No. M11820 CAS No. 1430230-83-3

LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    LY305
  • Note
    Research use only, not for human use.
  • Brief Description
    LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM.
  • Description
    LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM); displays little to no affinity for GR, PR and MR (Ki>800 nM); shows the desired muscle and prostate effects in a preclinical ORX rat model.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    LY 305 | LY-305
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor (AR)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1430230-83-3
  • Formula Weight
    264.753
  • Molecular Formula
    C14H17ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-chloro-4-(((1R,2R)-2-hydroxy-2-methylcyclopentyl)amino)-3-methylbenzonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Krishnan V, et al. Andrology. 2018 Mar 12. doi: 10.1111/andr.12479. 2. Saeed A, et al. J Med Chem. 2016 Jan 28;59(2):750-5.
molnova catalog
related products
  • AR antagonist 1

    AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.

  • ONC1-13B

    ONC1-13B is a potent androgen receptor (AR) antagonist with an ic50 in the range of 59-80 nM that inhibits PSA production in androgen-sensitive human PCa LNCaP cells.

  • Adrenosterone

    Adrenosterone is a steroid hormone with weak androgenic effect.