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LY305

CAS No. 1430230-83-3

LY305( LY 305 | LY-305 )

Catalog No. M11820 CAS No. 1430230-83-3

LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LY305
  • Note
    Research use only, not for human use.
  • Brief Description
    LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM.
  • Description
    LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM); displays little to no affinity for GR, PR and MR (Ki>800 nM); shows the desired muscle and prostate effects in a preclinical ORX rat model.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    LY 305 | LY-305
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor (AR)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1430230-83-3
  • Formula Weight
    264.753
  • Molecular Formula
    C14H17ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-chloro-4-(((1R,2R)-2-hydroxy-2-methylcyclopentyl)amino)-3-methylbenzonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Krishnan V, et al. Andrology. 2018 Mar 12. doi: 10.1111/andr.12479. 2. Saeed A, et al. J Med Chem. 2016 Jan 28;59(2):750-5.
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