
LY2090314
CAS No. 603288-22-8
LY2090314( LY2090314 | LY-2090314 | LY 2090314. )
Catalog No. M15255 CAS No. 603288-22-8
LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 51 | In Stock |
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5MG | 87 | In Stock |
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10MG | 140 | In Stock |
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25MG | 250 | In Stock |
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50MG | 410 | In Stock |
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100MG | 605 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameLY2090314
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NoteResearch use only, not for human use.
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Brief DescriptionLY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM.
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DescriptionLY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. Phase 2.
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In Vitro——
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In Vivo——
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SynonymsLY2090314 | LY-2090314 | LY 2090314.
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PathwayPI3K/Akt/mTOR signaling
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TargetGSK-3
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RecptorGSK-3α| GSK-3β
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number603288-22-8
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Formula Weight512.53
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Molecular FormulaC28H25FN6O3
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Purity>98% (HPLC)
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SolubilityEthanol: 2 mg/mL warmed (3.9 mM); DMSO: 100 mg/mL (195.11 mM)
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SMILESO=C(C(C1=CN2C3=C1C=C(F)C=C3CN(C(N4CCCCC4)=O)CC2)=C5C6=CN=C7C=CC=CN76)NC5=O
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Chemical Name3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brail LH, et al. J Clin Oncol, 2011, 29, abstr 3030.
molnova catalog



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LY2090314
LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM.