LY2090314

CAS No. 603288-22-8

LY2090314( LY2090314 | LY-2090314 | LY 2090314. )

Catalog No. M15255 CAS No. 603288-22-8

LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 51 In Stock
5MG 87 In Stock
10MG 140 In Stock
25MG 250 In Stock
50MG 410 In Stock
100MG 605 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    LY2090314
  • Note
    Research use only, not for human use.
  • Brief Description
    LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM.
  • Description
    LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. Phase 2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    LY2090314 | LY-2090314 | LY 2090314.
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    GSK-3α| GSK-3β
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    603288-22-8
  • Formula Weight
    512.53
  • Molecular Formula
    C28H25FN6O3
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 2 mg/mL warmed (3.9 mM); DMSO: 100 mg/mL (195.11 mM)
  • SMILES
    O=C(C(C1=CN2C3=C1C=C(F)C=C3CN(C(N4CCCCC4)=O)CC2)=C5C6=CN=C7C=CC=CN76)NC5=O
  • Chemical Name
    3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brail LH, et al. J Clin Oncol, 2011, 29, abstr 3030.
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