LOC14 ( —— )

Catalog No. M20192 CAS No. 877963-94-5

LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

LOC14
Note

Research use only not for human use.
Brief Description

LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM).
Description

LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM).
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PDI
Research Area

——
Indication

——

Chemical Information

CAS Number

877963-94-5
Formula Weight

317.4
Molecular Formula

C16H19N3O2S
Purity

>98% (HPLC)
Solubility

DMSO:25 mg/mL?(78.76 mM)
SMILES

O=C(C1CC1)N1CCN(Cn2sc3ccccc3c2=O)CC1
Chemical Name

2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-12-benzisothiazol-3(2H)-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kaplan A et al. Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2245-52.

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