Cart
sales@molnova.com
ISRIB-A15
CAS No. 1628478-12-5
ISRIB-A15( —— )
Catalog No. M35963 CAS No. 1628478-12-5
ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 92 | In Stock |
|
| 10MG | 151 | In Stock |
|
| 25MG | 242 | In Stock |
|
| 50MG | 384 | In Stock |
|
| 100MG | 575 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1237 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameISRIB-A15
-
NoteResearch use only, not for human use.
-
Brief DescriptionISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
-
DescriptionISR-IN-2 (Compound 47) is an inhibitor of the integrated stress response (EC50: 0.8 nM).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1628478-12-5
-
Formula Weight520.23
-
Molecular FormulaC22H22Cl4N2O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 2.5 mg/mL (4.81 mM; Ultrasonic (<60°C)
-
SMILESClc1ccc(OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc2ccc(Cl)c(Cl)c2)cc1Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80. ?
molnova catalog
related products
-
Salvianolic acid D
Salvianolic acid D and notoginseng triterpenes can promote EA-hy926 and expression of protein with protective effects on angiogenesis in EA-hy926 cells in vitro.
-
Arnidiol
Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn FArnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
-
6-Chloro-3-indolyl-β...
6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) is a chromogenic substrate for β-glucuronidase. 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) can be used in the histochemical analysis of β-glucuronidase activity.
