LLY-2707( LLY 2707 | LLY2707 )

Catalog No. M12388 CAS No. 1621865-33-5

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Product Name

LLY-2707
Note

Research use only, not for human use.
Brief Description

LLY-2707 (LLY 2707, LLY2707) is a novel potent, selective, nonsteroidal glucocorticoid receptor antagonist with Ki of 2.13 nM.
Description

LLY-2707 (LLY 2707, LLY2707) is a novel potent, selective, nonsteroidal glucocorticoid receptor antagonist with Ki of 2.13 nM; shows substantially lower potency at the other steroid receptors (AR, MR and PR); suppress amphetamine-induced increases in locomotor activity, reduces atypical antipsychotic-associated weight gain in rats.
In Vitro

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In Vivo

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Synonyms

LLY 2707 | LLY2707
Pathway

Endocrinology/Hormones
Target

GR
Recptor

GR
Research Area

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Indication

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CAS Number

1621865-33-5
Formula Weight

389.489
Molecular Formula

C20H24FN3O2S
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

N-(5-(tert-butyl)-3-(2-fluoro-5-methylpyridin-4-yl)-2-methyl-1H-indol-7-yl)methanesulfonamide

1. Sindelar DK, et al. J Pharmacol Exp Ther. 2014 Jan;348(1):192-201.

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