LDHA-IN-3

CAS No. 227010-33-5

LDHA-IN-3( —— )

Catalog No. M35158 CAS No. 227010-33-5

LDHA-IN-3 (1-(phenylseleno)-4-(trifluoromethyl) benzene) is a potent non-competitive lactate dehydrogenase (LDHA) inhibitor with an IC50 value of 145.2 nM.LDHA-IN-3 is a selenobenzene compound that can be used in cancer research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 76 Get Quote
5MG 116 Get Quote
10MG 186 Get Quote
25MG 380 Get Quote
50MG 566 Get Quote
100MG 788 Get Quote
500MG 1602 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    LDHA-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    LDHA-IN-3 (1-(phenylseleno)-4-(trifluoromethyl) benzene) is a potent non-competitive lactate dehydrogenase (LDHA) inhibitor with an IC50 value of 145.2 nM.LDHA-IN-3 is a selenobenzene compound that can be used in cancer research.
  • Description
    LDHA-IN-3, as a selenobenzene compound, is a potent, noncompetitive lactate dehydrogenase (LDHA) inhibitor (IC50=145.2 nM). LDHA-IN-3 can be used for the research of cancer.
  • In Vitro
    Cell Viability Assay Cell Line:MCF-7 cells Concentration:0~500 μM Incubation Time:48 hours Result:Showed cytotoxic effect.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    Dehydrogenase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    227010-33-5
  • Formula Weight
    301.17
  • Molecular Formula
    C13H9F3Se
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (332.04 mM; Ultrasonic )
  • SMILES
    [Se](C1=CC=C(C(F)(F)F)C=C1)C2=CC=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim EY, et al. A Novel Lactate Dehydrogenase Inhibitor, 1-(Phenylseleno)-4-(Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death. Sci Rep. 2019;9(1):3969. Published 2019 Mar 8.
molnova catalog
related products
  • DHODH-IN-12

    DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.

  • Trilostane

    Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.

  • Nitrophenide

    Nitrophenide inhibits mannitol-1-phosphate dehydrogenase (M1PDH), which catalyzes the committed enzymatic step in the mannitol cycle. Nitrophenide can be used as an anticoccidial agent.