L-allo-Isoleucine

CAS No. 1509-34-8

L-allo-Isoleucine ( (3R)-LS-Isoleucine;L(+)-Alloisoleucine )

Catalog No. M20000 CAS No. 1509-34-8

L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine which is derived from L-isoleucine in vivo can be used for the diagnosis of maple syrup urine disease (MSUD) a genetic disorder.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 35 In Stock
50MG 50 In Stock
100MG 72 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    L-allo-Isoleucine
  • Note
    Research use only not for human use.
  • Brief Description
    L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine which is derived from L-isoleucine in vivo can be used for the diagnosis of maple syrup urine disease (MSUD) a genetic disorder.
  • Description
    L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine which is derived from L-isoleucine in vivo can be used for the diagnosis of maple syrup urine disease (MSUD) a genetic disorder. Indeed plasma L-alloisoleucine levels above 5 μmol/L is the most specific and most sensitive diagnostic marker for all forms of MSUD.
  • Synonyms
    (3R)-LS-Isoleucine;L(+)-Alloisoleucine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1509-34-8
  • Formula Weight
    131.17
  • Molecular Formula
    C6H13NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC[C@@H](C)[C@H](N)C(O)=O
  • Chemical Name
    (2S3R)-2-Amino-3-methylpentanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schadewaldt P et al. Significance of L-alloisoleucine in plasma for diagnosis of maple syrup urine disease. Clin Chem. 1999 Oct;45(10):1734-40.
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