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NIH-12848
CAS No. 959551-10-1
NIH-12848 ( NIH-12848;NCGC00012848-02. )
Catalog No. M17694 CAS No. 959551-10-1
NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 110 | In Stock |
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| 25MG | 214 | In Stock |
|
| 50MG | 377 | In Stock |
|
| 100MG | 537 | In Stock |
|
| 500MG | 1152 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNIH-12848
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NoteResearch use only, not for human use.
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Brief DescriptionNIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.
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DescriptionNIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.
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SynonymsNIH-12848;NCGC00012848-02.
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorPI5P4Kγ
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Research Area——
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Indication——
Chemical Information
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CAS Number959551-10-1
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Formula Weight385.41
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Molecular FormulaC20H14F3N3S
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Purity98%
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SolubilityDMSO : ≥ 28 mg/mL; 72.65 mM
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SMILESFC(F)(F)c1ccccc1c1nc2ccccc2c(NCc2cccs2)n1
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Chemical NameN-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Clarke JH,et al.Biochem J. 2015 Mar 1;466(2):359-67.
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