Cart
sales@molnova.com
NIH-12848
CAS No. 959551-10-1
NIH-12848 ( NIH-12848;NCGC00012848-02. )
Catalog No. M17694 CAS No. 959551-10-1
NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
|
| 5MG | 77 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 214 | In Stock |
|
| 50MG | 377 | In Stock |
|
| 100MG | 537 | In Stock |
|
| 500MG | 1152 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNIH-12848
-
NoteResearch use only, not for human use.
-
Brief DescriptionNIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.
-
DescriptionNIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.
-
SynonymsNIH-12848;NCGC00012848-02.
-
PathwayGPCR/G Protein
-
TargetNeurokinin Receptor
-
RecptorPI5P4Kγ
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number959551-10-1
-
Formula Weight385.41
-
Molecular FormulaC20H14F3N3S
-
Purity98%
-
SolubilityDMSO : ≥ 28 mg/mL; 72.65 mM
-
SMILESFC(F)(F)c1ccccc1c1nc2ccccc2c(NCc2cccs2)n1
-
Chemical NameN-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Clarke JH,et al.Biochem J. 2015 Mar 1;466(2):359-67.
molnova catalog
related products
-
SB-222200
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM).
-
Hemokinin 1 (mouse)
Hemokinin 1 (mouse) is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 receptor.
-
Aprepitant
A potent, orally active, long-acting human NK-1 receptor (substance P receptor) antagonist with IC50 of 0.09 nM.
