NIH-12848 ( NIH-12848;NCGC00012848-02. )

Catalog No. M17694 CAS No. 959551-10-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

NIH-12848
Note

Research use only, not for human use.
Brief Description

NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.
Description

NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.
Synonyms

NIH-12848;NCGC00012848-02.
Pathway

GPCR/G Protein
Target

Neurokinin Receptor
Recptor

PI5P4Kγ
Research Area

——
Indication

——

CAS Number

959551-10-1
Formula Weight

385.41
Molecular Formula

C20H14F3N3S
Purity

98%
Solubility

DMSO : ≥ 28 mg/mL; 72.65 mM
SMILES

FC(F)(F)c1ccccc1c1nc2ccccc2c(NCc2cccs2)n1
Chemical Name

N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine

1. Clarke JH,et al.Biochem J. 2015 Mar 1;466(2):359-67.

Calculator

molnova catalog