KuWal151

CAS No.

KuWal151 ( KuWal 151 )

Catalog No. M16943 CAS No.

KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    KuWal151
  • Note
    Research use only, not for human use.
  • Brief Description
    KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.
  • Description
    KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively; shows no activity against CLK3 (IC50>10 uM), exhibits selectivity versus DYRK1A and other DYRK kinases; displays a potent antiproliferative activity in an array of cultured cancer cell lines (HCT-116 cell GI50=191 nM).
  • Synonyms
    KuWal 151
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CLK
  • Recptor
    CLK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    --
  • Formula Weight
    282.73
  • Molecular Formula
    C16H11ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1NCC2=C1C3=C(C=C2)C(C4=CC=CC(Cl)=C4)=CN3
  • Chemical Name
    3-(3-chlorophenyl)-6,7-dihydropyrrolo[3,4-g]indol-8(1H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Walter A, et al. PLoS One. 2018 May 3;13(5):e0196761.
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  • KuWal151

    KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.