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KuWal151
CAS No.
KuWal151 ( KuWal 151 )
Catalog No. M16943 CAS No.
KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameKuWal151
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NoteResearch use only, not for human use.
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Brief DescriptionKuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.
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DescriptionKuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively; shows no activity against CLK3 (IC50>10 uM), exhibits selectivity versus DYRK1A and other DYRK kinases; displays a potent antiproliferative activity in an array of cultured cancer cell lines (HCT-116 cell GI50=191 nM).
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SynonymsKuWal 151
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PathwayCell Cycle/DNA Damage
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TargetCLK
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RecptorCLK
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight282.73
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Molecular FormulaC16H11ClN2O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1NCC2=C1C3=C(C=C2)C(C4=CC=CC(Cl)=C4)=CN3
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Chemical Name3-(3-chlorophenyl)-6,7-dihydropyrrolo[3,4-g]indol-8(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Walter A, et al. PLoS One. 2018 May 3;13(5):e0196761.
molnova catalog
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KH-CB19
KH-CB19 is a potent and highly specific inhibitor of CDC2-like kinase isoforms 1 and 4 (CLK1/CLK4) with IC50 of 20 nM (CLK1).
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KuWal151
KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.
