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KIN-1400

CAS No. 446826-86-4

KIN-1400( KIN1400 | KIN 1400 )

Catalog No. M14529 CAS No. 446826-86-4

A potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    KIN-1400
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression.
  • Description
    A potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression; shows antiviral activity against a broad range of RNA viruses, including dengue virus, and hepatitis C virus, as well as viruses of the families Filoviridae (Ebola virus), Orthomyxoviridae (influenza A virus), Arenaviridae (Lassa virus), and Paramyxoviridae (respiratory syncytial virus, Nipah virus).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    KIN1400 | KIN 1400
  • Pathway
    Immunology/Inflammation
  • Target
    RLR
  • Recptor
    RLR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    446826-86-4
  • Formula Weight
    449.476
  • Molecular Formula
    C24H17F2N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC1=C2N=CC=CC2=CC=C1C(NC3=NC4=CC=CC=C4S3)C5=CC=C(OC(F)F)C=C5
  • Chemical Name
    7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pattabhi S, et al. J Virol. 2015 Dec 16;90(5):2372-87.
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