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KHK-IN-1

CAS No. 1303469-70-6

KHK-IN-1 ( Ketohexokinase inhibitor 8; KHK-IN-8 )

Catalog No. M26731 CAS No. 1303469-70-6

KHK-IN-1 is a reversible and ATP-competitive inhibitor of ketohexokinase (KHK) with IC50 of 12 nM. In the ATP-binding region of KHK, KHK-IN-1 interacts with Asp-27B.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    KHK-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    KHK-IN-1 is a reversible and ATP-competitive inhibitor of ketohexokinase (KHK) with IC50 of 12 nM. In the ATP-binding region of KHK, KHK-IN-1 interacts with Asp-27B.
  • Description
    KHK-IN-1 is a reversible and ATP-competitive inhibitor of ketohexokinase (KHK) with IC50 of 12 nM. In the ATP-binding region of KHK, KHK-IN-1 interacts with Asp-27B.
  • Synonyms
    Ketohexokinase inhibitor 8; KHK-IN-8
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GLP-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1303469-70-6
  • Formula Weight
    422.6
  • Molecular Formula
    C21H26N8S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CSc1ccccc1Nc1nc(nc2c(NCC3CC3)ncnc12)N1CCNCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Elahi D, et al. GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 2008;16(7):1501-1509.
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