KF38789

Research use only, not for human use.

KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.

KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.(In Vitro):KF 38789, inhibited the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 microM. Cell adhesion to both E-selectin-Ig and L-selectin-Ig were not affected even by 100 microM of KF 38789. Moreover, KF 38789 inhibited P-selectin-induced superoxide production from human polymorphonuclear cells. Intravenously injected KF 38789 significantly inhibited the TG-induced accumulation of leukocytes in the mouse peritoneal cavity (p<0.01).(In Vivo):KF 38789 significantly reduced mechanical allodynia in the facial carrageenan-injected mice.

KF 38789

Others

Other Targets

fatty acid 3 receptor (FA3R)

——

——

257292-29-8

375.4

C19H21NO5S

>98% (HPLC)

——

COc1ccc(C2CC(=NCCS2)c2c(O)cc(C)oc2=O)c(OC)c1

——

(-20℃)

With Ice Pack

≥ 2 years