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KF38789
CAS No. 257292-29-8
KF38789 ( KF 38789 )
Catalog No. M27643 CAS No. 257292-29-8
KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 111 | Get Quote |
|
| 10MG | 177 | Get Quote |
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| 25MG | 338 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameKF38789
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NoteResearch use only, not for human use.
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Brief DescriptionKF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.
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DescriptionKF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.(In Vitro):KF 38789, inhibited the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 microM. Cell adhesion to both E-selectin-Ig and L-selectin-Ig were not affected even by 100 microM of KF 38789. Moreover, KF 38789 inhibited P-selectin-induced superoxide production from human polymorphonuclear cells. Intravenously injected KF 38789 significantly inhibited the TG-induced accumulation of leukocytes in the mouse peritoneal cavity (p<0.01).(In Vivo):KF 38789 significantly reduced mechanical allodynia in the facial carrageenan-injected mice.
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SynonymsKF 38789
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PathwayOthers
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TargetOther Targets
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Recptorfatty acid 3 receptor (FA3R)
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Research Area——
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Indication——
Chemical Information
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CAS Number257292-29-8
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Formula Weight375.4
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Molecular FormulaC19H21NO5S
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Purity>98% (HPLC)
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Solubility——
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SMILESCOc1ccc(C2CC(=NCCS2)c2c(O)cc(C)oc2=O)c(OC)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Getachew B, et al. Butyrate Protects Against Salsolinol-Induced Toxicity in SH-SY5Y Cells: Implication for Parkinson's Disease. Neurotox Res. 2020 Oct;38(3):596-602.
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