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KD025
CAS No. 911417-87-3
KD025 ( SLx-2119; SLx2119; SLx 2119; KD 025 )
Catalog No. M19254 CAS No. 911417-87-3
KD025 is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 37 | In Stock |
|
| 5MG | 60 | In Stock |
|
| 10MG | 83 | In Stock |
|
| 25MG | 152 | In Stock |
|
| 50MG | 237 | In Stock |
|
| 100MG | 356 | In Stock |
|
| 500MG | 849 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKD025
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NoteResearch use only, not for human use.
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Brief DescriptionKD025 is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).
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DescriptionSLx-2119, also known as KD-025, is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 μM, respectively).
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SynonymsSLx-2119; SLx2119; SLx 2119; KD 025
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PathwayOthers
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TargetOther Targets
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RecptorROCK2; ROCK2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number911417-87-3
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Formula Weight452.51
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Molecular FormulaC26H24N6O2
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Purity98%
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SolubilityDMSO : ≥ 29 mg/mL; 64.09 mM
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SMILESC(=O)(COc1cc(ccc1)c1nc2c(c(n1)Nc1cc3cn[nH]c3cc1)cccc2)NC(C)C
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Chemical Name2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lee JH, et al. Ann Clin Transl Neurol. 2014, 1(1), 2-14.
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