KD025

CAS No. 911417-87-3

KD025 ( SLx-2119; SLx2119; SLx 2119; KD 025 )

Catalog No. M19254 CAS No. 911417-87-3

KD025 is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 37 In Stock
5MG 60 In Stock
10MG 83 In Stock
25MG 152 In Stock
50MG 237 In Stock
100MG 356 In Stock
500MG 849 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    KD025
  • Note
    Research use only, not for human use.
  • Brief Description
    KD025 is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).
  • Description
    SLx-2119, also known as KD-025, is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 μM, respectively).
  • Synonyms
    SLx-2119; SLx2119; SLx 2119; KD 025
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ROCK2; ROCK2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    911417-87-3
  • Formula Weight
    452.51
  • Molecular Formula
    C26H24N6O2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 29 mg/mL; 64.09 mM
  • SMILES
    C(=O)(COc1cc(ccc1)c1nc2c(c(n1)Nc1cc3cn[nH]c3cc1)cccc2)NC(C)C
  • Chemical Name
    2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lee JH, et al. Ann Clin Transl Neurol. 2014, 1(1), 2-14.
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