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JNJ-63533054
CAS No. 1802326-66-4
JNJ-63533054 ( JNJ 63533054; JNJ63533054; JNJ-63533054 )
Catalog No. M17383 CAS No. 1802326-66-4
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 54 | In Stock |
|
| 10MG | 82 | In Stock |
|
| 25MG | 176 | In Stock |
|
| 50MG | 311 | In Stock |
|
| 100MG | 461 | In Stock |
|
| 500MG | 972 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJNJ-63533054
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NoteResearch use only, not for human use.
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Brief DescriptionJNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
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DescriptionJNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain and cell penetrant. JNJ 63533054 is selective for GPR139 over a panel of GPCRs, ion channels and transporters, including GPR142 and is orally bioavailable.
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SynonymsJNJ 63533054; JNJ63533054; JNJ-63533054
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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RecptorhGPR139
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1802326-66-4
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Formula Weight316.78
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Molecular FormulaC17H17ClN2O2
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Purity98%
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SolubilityDMSO : ≥ 50 mg/mL 157.84 mM; H2O : < 0.1 mg/mL
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SMILESC[C@@H](c1ccccc1)NC(=O)CNC(=O)c1cc(ccc1)Cl
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Chemical Name3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20;6(9):1015-8.
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