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Home - Products - Angiogenesis - Adrenergic Receptor - JNJ-63533054

JNJ-63533054

CAS No. 1802326-66-4

JNJ-63533054( JNJ 63533054 | JNJ63533054 | JNJ-63533054 )

Catalog No. M17383 CAS No. 1802326-66-4

JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    JNJ-63533054
  • Note
    Research use only, not for human use.
  • Brief Description
    JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
  • Description
    JNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain and cell penetrant. JNJ 63533054 is selective for GPR139 over a panel of GPCRs, ion channels and transporters, including GPR142 and is orally bioavailable.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    JNJ 63533054 | JNJ63533054 | JNJ-63533054
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    hGPR139
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1802326-66-4
  • Formula Weight
    316.78
  • Molecular Formula
    C17H17ClN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 50 mg/mL 157.84 mM; H2O : < 0.1 mg/mL
  • SMILES
    C[C@@H](c1ccccc1)NC(=O)CNC(=O)c1cc(ccc1)Cl
  • Chemical Name
    3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20;6(9):1015-8.
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