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JMJD7-IN-1
CAS No. 311316-96-8
JMJD7-IN-1( Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester )
Catalog No. M24241 CAS No. 311316-96-8
JMJD7-IN-1 is a potent?JMJD7?inhibitor, with an?IC50?of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 43 | In Stock |
|
| 5MG | 72 | In Stock |
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| 10MG | 125 | In Stock |
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| 25MG | 259 | In Stock |
|
| 50MG | 403 | In Stock |
|
| 100MG | 592 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJMJD7-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionJMJD7-IN-1 is a potent?JMJD7?inhibitor, with an?IC50?of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.
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DescriptionJMJD7-IN-1 is a potent?JMJD7?inhibitor, with an?IC50?of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.
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In VitroJMJD7-IN-1 (0.1-1000 μM) dose-dependently inhibits the activity of JMJD7, with an IC50 of 6.62 μM.JMJD7-IN-1 efficiently binds to JMJD7, with an IC50 of 3.80 μM.JMJD7-IN-1 (72 h) inhibits the growth of T-47d, SK-BR-3, Jurkat and Hela cells, with IC50s of 9.40 μM, 13.26 μM, 15.03 μM and 16.14 μM, respectively.
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In Vivo——
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SynonymsBenzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester
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PathwayOthers
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TargetOther Targets
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RecptorJMJD7
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Research Area——
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Indication——
Chemical Information
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CAS Number311316-96-8
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Formula Weight363.15
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Molecular FormulaC16H8Cl2N2O4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C(OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1)C3=CC=C(Cl)C=C3Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang W, et, al. Discovery of JMJD7 inhibitors with the aid of virtual screening and bioactivity evaluation. Bioorg Med Chem Lett. 2021 May 25;45:128139.
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