J147 ( J147; J 147; J-147 )

Catalog No. M10519 CAS No. 1146963-51-0

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Datasheet

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HPLC

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Product Name

J147
Note

Research use only, not for human use.
Brief Description

J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF).
Description

J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF).
Synonyms

J147; J 147; J-147
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

BDNF
Research Area

Neurological Disease
Indication

——

CAS Number

1146963-51-0
Formula Weight

350.34
Molecular Formula

C18H17F3N2O2
Purity

>98%(HPLC)
Solubility

Soluble in DMSO
SMILES

O=C(N(C1=CC=C(C)C=C1C)/N=C/C2=CC=CC(OC)=C2)C(F)(F)F
Chemical Name

2,2,2-Trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

1.Lapchak PA, et al. J Neurol Neurophysiol. 2013 Aug;4(3). pii: 158.

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