Itaconate-alkyne

CAS No. 2454181-83-8

Itaconate-alkyne ( ITalk )

Catalog No. M28361 CAS No. 2454181-83-8

Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 147 Get Quote
10MG 237 Get Quote
25MG 484 Get Quote
50MG 700 Get Quote
100MG 981 Get Quote
500MG 1962 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Itaconate-alkyne
  • Note
    Research use only, not for human use.
  • Brief Description
    Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.
  • Description
    Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.(In Vitro):Itaconate-alkyne can capture itaconate targets including DNA damage-binding protein 1 (DDB1), Gelsolin (GSN), ATP-citrate synthase (ACLY) and Adenylate kinase 2 (AK2) in inflammatory macrophages.
  • Synonyms
    ITalk
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2454181-83-8
  • Formula Weight
    238.3
  • Molecular Formula
    C13H18O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)C(=C)CC(=O)OCCCCCCC#C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Daly JW, et al. Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. Biochem Pharmacol. 1986 Aug 1;35(15):2467-81.
molnova catalog
related products
  • Praeruptorin B(b)

    Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway.

  • Alisporivir intermed...

    Alisporivir intermediate-1 is an intermediate in the synthesis of Alisporivir and is used for the treatment of inflammatory and viral diseases.

  • Coniferyl alcohol b

    Coniferyl alcohol restores the growth of KI-treated BY-2 cells and N. benthamiana seedlings, at high concentrations is toxic to plant cells.