Ionomycin( —— )

Catalog No. M36477 CAS No. 56092-81-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Ionomycin
Note

Research use only, not for human use.
Brief Description

Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+).
Description

Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC).
In Vitro

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In Vivo

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Synonyms

——
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel
Research Area

——
Indication

——

CAS Number

56092-81-0
Formula Weight

709.01
Molecular Formula

C41H72O9
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (141.04 mM; Ultrasonic ) Ethanol : 100 mg/mL (141.04 mM; Ultrasonic)
SMILES

[H][C@@]1(C[C@H](O)[C@H](C)[C@H](O)[C@H](C)\C=C\C[C@@H](C)C[C@@H](C)C(\O)=C\C(=O)[C@@H](C)C[C@@H](C)C[C@H](C)CCC(O)=O)CC[C@](C)(O1)[C@@]1([H])CC[C@](C)(O1)[C@@H](C)O
Chemical Name

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1. Liu C,et al. Characterization of ionomycin as a calcium ionophore. J Biol Chem. 1978 Sep 10;253(17):5892-4.?

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