
Infree
CAS No. 85801-02-1
Infree( —— )
Catalog No. M21168 CAS No. 85801-02-1
Infree is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 33 | Get Quote |
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10MG | 45 | Get Quote |
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25MG | 69 | Get Quote |
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50MG | 110 | Get Quote |
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100MG | 165 | Get Quote |
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200MG | 248 | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameInfree
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NoteResearch use only, not for human use.
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Brief DescriptionInfree is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).
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DescriptionInfree is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).
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In VitroIndometacin farnesil (IMF) is a newly synthesized prodrug of indomethacin designed to reduce the occurrence of side-effects by esterification of the carboxyl group of indomethacin with farnesol. This modification is intended to decrease the extraction and subsequent rapid metabolism of the drug by the liver, so that lymphatic absorption would become a major route, and it was also anticipates that hydrolytic enzymes present in plasma and tissues, including inflamed tissue, would release indomethacin effectively from IMF.
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In VivoIndomethacin farnesil (IMF) can effectively release indomethacin when administered locally. Animal Model:Rats.Dosage:50 nmol a rat paw.Administration:Once.Result:Reduced the level of PGE2 in a dose dependent manner.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorothers
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Research Area——
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Indication——
Chemical Information
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CAS Number85801-02-1
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Formula Weight562.14
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Molecular FormulaC34H40ClNO4
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Purity>98% (HPLC)
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Solubility——
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SMILESClc1ccc(cc1)C(=O)n3c2ccc(cc2c(CC(=O)OC\C=C(/C)CC\C=C(/C)CC\C=C(/C)C)c3C)OC
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Chemical Name3711-Trimethyldodeca-2610-trien-1-yl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ono K Hashimoto T Satoh T . Eosinophilic Pustular Folliculitis Clinically Presenting as Orofacial Granuloma: Successful Treatment with Indomethacin But Not Ibuprofen[J]. Acta Dermato Venereologica 2015 95(3):361-362.
molnova catalog



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