
Indophagolin
CAS No. 1207660-00-1
Indophagolin( —— )
Catalog No. M23377 CAS No. 1207660-00-1
Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM.?
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 142 | In Stock |
![]() ![]() |
5MG | 210 | In Stock |
![]() ![]() |
10MG | 316 | In Stock |
![]() ![]() |
25MG | 534 | In Stock |
![]() ![]() |
50MG | 761 | In Stock |
![]() ![]() |
100MG | 1053 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameIndophagolin
-
NoteResearch use only, not for human use.
-
Brief DescriptionIndophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM.?
-
DescriptionIndophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM.?Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.
-
In VitroIndophagolin (10 μM) inhibits autophagosome formation in MCF7 cells.
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
Recptorautophagy|P2X1|P2X3|P2X4
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1207660-00-1
-
Formula Weight523.75
-
Molecular FormulaC19H15BrClF3N2O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESO=S(C1=CC2=C(C=C1Br)CCN2C(C3CC3)=O)(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Carnero Corrales MA, et al. Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin [published online ahead of print, 2021 Mar 9]. Cell Chem Biol. 2021;S2451-9456(21)00102-1.
molnova catalog



related products
-
AUTEN-99 hydrobromid...
A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
-
Gemcitabine (elaidat...
Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity.?
-
CC214-1
CC214-1 is an mTOR inhibitor with potential anticancer activity, inhibits protein translation, and induces autophagy.