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Indometacin
CAS No. 53-86-1
Indometacin ( Indomethacin; Indometacin; Indocin )
Catalog No. M14921 CAS No. 53-86-1
Indomethacin is a non-steroidal antiinflammatory agent (NSAIA) with antiinflammatory, analgesic and antipyretic activity.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 45 | In Stock |
|
Biological Information
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Product NameIndometacin
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NoteResearch use only, not for human use.
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Brief DescriptionIndomethacin is a non-steroidal antiinflammatory agent (NSAIA) with antiinflammatory, analgesic and antipyretic activity.
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DescriptionIndomethacin is a non-steroidal antiinflammatory agent (NSAIA) with antiinflammatory, analgesic and antipyretic activity. Its pharmacological effect is thought to be mediated through inhibition of the enzyme cyclooxygenase (COX), the enzyme responsible for catalyzes the rate-limiting step in prostaglandin synthesis via the arachidonic acid pathway.
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SynonymsIndomethacin; Indometacin; Indocin
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX-1; COX-1; COX-2; PDE2; PLA2
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number53-86-1
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Formula Weight357.79
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Molecular FormulaC19H16ClNO4
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Purity>98%(HPLC)
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SolubilityEthanol: 24 mg/mL (67.07 mM); DMSO: 72 mg/mL (201.23 mM)
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SMILESO=C(O)CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3
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Chemical Name2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mitchell JA, et al. Proc Natl Acad Sci U S A. 1993, 90(24), 11693-11697.
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