Indapamide

Research use only, not for human use.

Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.

Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.(In Vitro):Indapamide (0.1-500 mg/L; 20min) reduces total insulin secretory response to glucose infusions in isolated perfused rat pancreas.Indapamide (1-100 μM) increases osteoblast proliferation and decreased bone resorption.(In Vivo):Indapamide (1 mg/kg/d; gastric gavage for 8 weeks) lowers blood pressure in spontaneously hypertensive rats (SHRs).Indapamide (10 mg/kg/d) decreases pressor response to oxotremorine, noradrenaline, and tyramine in rats.

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(±)-Indapamide

Cell Cycle/DNA Damage

Potassium Channel

Potassium Channel

Cardiovascular Disease

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26807-65-8

365.84

C16H16ClN3O3S

>98% (HPLC)

Ethanol: 73 mg/mL (199.54 mM); DMSO: 73 mg/mL (199.54 mM)

O=C(NN1C(C)CC2=C1C=CC=C2)C3=CC=C(Cl)C(S(=O)(N)=O)=C3

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(-20℃)

With Ice Pack

≥ 2 years