Cart
sales@molnova.com
Indapamide
CAS No. 26807-65-8
Indapamide( (±)-Indapamide )
Catalog No. M13818 CAS No. 26807-65-8
Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 43 | In Stock |
|
Biological Information
-
Product NameIndapamide
-
NoteResearch use only, not for human use.
-
Brief DescriptionIndapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
-
DescriptionIndapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.(In Vitro):Indapamide (0.1-500 mg/L; 20min) reduces total insulin secretory response to glucose infusions in isolated perfused rat pancreas.Indapamide (1-100 μM) increases osteoblast proliferation and decreased bone resorption.(In Vivo):Indapamide (1 mg/kg/d; gastric gavage for 8 weeks) lowers blood pressure in spontaneously hypertensive rats (SHRs).Indapamide (10 mg/kg/d) decreases pressor response to oxotremorine, noradrenaline, and tyramine in rats.
-
In Vitro——
-
In Vivo——
-
Synonyms(±)-Indapamide
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorPotassium Channel
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number26807-65-8
-
Formula Weight365.84
-
Molecular FormulaC16H16ClN3O3S
-
Purity>98% (HPLC)
-
SolubilityEthanol: 73 mg/mL (199.54 mM); DMSO: 73 mg/mL (199.54 mM)
-
SMILESO=C(NN1C(C)CC2=C1C=CC=C2)C3=CC=C(Cl)C(S(=O)(N)=O)=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Pedersen EB, et al. Eur J Clin Pharmacol, 1984. 26(5): p. 543-7.
molnova catalog
related products
-
Glyburide
Glibenclamide(Glyburide) is a sulfonylurea compound that modulates insulin production.
-
Retigabine
Retigabine (Ezogabine; D23129) is a Kv7.2-7.5 (KCNQ2-5) neuronal potassium channel opener witrh anticonvulsant activity.
-
Dronedarone
A multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
