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Dronedarone
CAS No. 141626-36-0
Dronedarone ( SR-33589 )
Catalog No. M11734 CAS No. 141626-36-0
A multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 42 | In Stock |
|
| 50MG | 124 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDronedarone
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NoteResearch use only, not for human use.
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Brief DescriptionA multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
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DescriptionA multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats; reduces significantly the incidence of ventricular fibrillation (VF) in rats; mainly used for treatment of cardiac arrhythmias.Heart Arrhythmia Approved
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SynonymsSR-33589
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorPotassium Channel;Sodium channel;Calcium channel
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Research AreaCardiovascular Disease
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IndicationHeart Arrhythmia
Chemical Information
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CAS Number141626-36-0
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Formula Weight556.76
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Molecular FormulaC31H44N2O5S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCS(=O)(NC1=CC2=C(OC(CCCC)=C2C(C3=CC=C(OCCCN(CCCC)CCCC)C=C3)=O)C=C1)=O
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Chemical NameMethanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Aimond F, et al. J Pharmacol Exp Ther. 2000 Jan;292(1):415-24.
2. Sun W, et al. Circulation. 1999 Nov 30;100(22):2276-81.
3. Manakshe G, et al. Indian Heart J. 2012 Mar-Apr;64(2):182-6.
2. Sun W, et al. Circulation. 1999 Nov 30;100(22):2276-81.
3. Manakshe G, et al. Indian Heart J. 2012 Mar-Apr;64(2):182-6.
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Dronedarone
A multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
