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Imexon

CAS No. 59643-91-3

Imexon ( Amplimexon;BM 06002 )

Catalog No. M15211 CAS No. 59643-91-3

A 2-cyanoaziridine derivative with antitumor activity in some types of cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Imexon
  • Note
    Research use only, not for human use.
  • Brief Description
    A 2-cyanoaziridine derivative with antitumor activity in some types of cancer.
  • Description
    A 2-cyanoaziridine derivative with antitumor activity in some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma; induces mitochondrial oxidation and induces apoptosis via a pathway involving cleaved caspase-3, caspase-9, and/or caspase-8; an apoptosis inducer agent.Blood Cancer Phase 2 Clinical
  • Synonyms
    Amplimexon;BM 06002
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    Cancer
  • Indication
    Blood cancer

Chemical Information

  • CAS Number
    59643-91-3
  • Formula Weight
    111.10
  • Molecular Formula
    C4H5N3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1N2CC2C(N)=N1
  • Chemical Name
    4-Amino-1,3-diazabicyclo[3.1.0]hex-3-en-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ziegler AE, et al. Exp Pathol (Jena). 1977;14(6):321-7.
2. Hersh EM, et al. J Natl Cancer Inst. 1992 Aug 19;84(16):1238-44.
3. Baker AF, et al. Clin Cancer Res. 2007 Jun 1;13(11):3388-94.
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