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Iganidipine
CAS No. 119687-33-1
Iganidipine( —— )
Catalog No. M33383 CAS No. 119687-33-1
Iganidipine（NKY 722） is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 1064 | Get Quote |
|
| 5MG | 1710 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIganidipine
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NoteResearch use only, not for human use.
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Brief DescriptionIganidipine（NKY 722） is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.
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DescriptionIganidipine is a Ca2+ antagonist.
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In Vitro——
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In VivoIganidipine (0.03% solution) significantly increases optic nerve head (ONH) tissue blood velocity (NBONH)by 8 to 10% in treated eyes after a single administration (p<0.05) or by 18 to 35% after 7-, 14-, or 21-day twicedaily administration in rabbits (p<0.05). In monkeys, 0.03% and 0.1% Iganidipine significantly increases NBONH in treated eyes by 20 and 41% after 7-day (p<0.05) twice-daily administration, respectively.
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number119687-33-1
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Formula Weight526.62
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Molecular FormulaC28H38N4O6
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=C(C)NC(C)=C(C1C2=CC([N+]([O-])=O)=CC=C2)C(OCC(C)(CN3CCN(CC3)CC=C)C)=O)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ishii K, et al. Iganidipine, a new water-soluble Ca2+ antagonist: ocular and periocular penetration after instillation. Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1169-77.?
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