Icotinib

CAS No. 610798-31-7

Icotinib ( —— )

Catalog No. M15296 CAS No. 610798-31-7

Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 52 In Stock
5MG 87 In Stock
10MG 141 In Stock
25MG 267 In Stock
50MG 500 In Stock
100MG 674 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Icotinib
  • Note
    Research use only, not for human use.
  • Brief Description
    Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM.
  • Description
    Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    610798-31-7
  • Formula Weight
    391.42
  • Molecular Formula
    C22H21N3O4
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:78 mg/mL (199.27 mM); Ethanol:7 mg/mL (17.88 mM); Water:<1 mg/mL (<1 mM)
  • SMILES
    C#CC1=CC(NC2=NC=NC3=CC4=C(OCCOCCOCCO4)C=C23)=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tan F, et al. Lung Y, 2012, 76(2), 177-182.
molnova catalog
related products
  • PD-161570

    PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.

  • Tarloxotinib bromide

    Tarloxotinib bromide is an irreversible inhibitor of EGFR/HER2.

  • O-Nornuciferine

    O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.