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Iclepertin
CAS No. 1421936-85-7
Iclepertin( —— )
Catalog No. M34912 CAS No. 1421936-85-7
Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 344 | Get Quote |
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| 5MG | 534 | Get Quote |
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| 10MG | 847 | Get Quote |
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| 25MG | 1831 | Get Quote |
|
| 50MG | 3008 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIclepertin
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NoteResearch use only, not for human use.
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Brief DescriptionIclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease.
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DescriptionIclepertin (BI-425809) is a potent, selective and orally active glycine transporter 1 (GlyT1) inhibitor. Iclepertin is inactive against GlyT2. Iclepertin can be used for Alzheimer disease and schizophrenia research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetGlyT
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RecptorGlyT
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Research Area——
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Indication——
Chemical Information
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CAS Number1421936-85-7
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Formula Weight512.42
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Molecular FormulaC20H18F6N2O5S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 11.36 mg/mL (22.17 mM; Ultrasonic (<60°C)
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SMILES[H][C@@]12C[C@@]1(CN(C2)C(=O)c1cc(ccc1O[C@H](C)C(F)(F)F)S(C)(=O)=O)c1cc(on1)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Holger Rosenbrock, et al. Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies. Clin Transl Sci. 2018 Nov;11(6):616-623.?
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