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Ibrutinib-biotin
CAS No. 1599432-18-4
Ibrutinib-biotin( —— )
Catalog No. M12294 CAS No. 1599432-18-4
A chemical probe that consists of Ibrutinib linked to biotin via a long chain linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameIbrutinib-biotin
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NoteResearch use only, not for human use.
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Brief DescriptionA chemical probe that consists of Ibrutinib linked to biotin via a long chain linker.
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DescriptionA chemical probe that consists of Ibrutinib linked to biotin via a long chain linker, has IC50 of 0.755-1.02 nM for Btk kinase; extracted from patent WO2014059368A1 Compound 1-5.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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TargetBTK
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RecptorBTK
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1599432-18-4
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Formula Weight1097.374
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Molecular FormulaC56H80N12O9S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCN(CCCCNC(=O)CCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2)CC=CC(=O)N3CCCC(C3)N4C5=NC=NC(=C5C(=N4)C6=CC=C(C=C6)OC7=CC=CC=C7)N
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Chemical NamePentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-4-oxo-2-buten-1-yl]methylamino]butyl]-N5-[19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-4,7,10-trioxa-14-azanonadec-1-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Betty Y. CHANG, et al. Companion diagnostics for tec family kinase inhibitor therapy. WO 2014059368 A1.
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