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IWP-O1
CAS No. 2074607-48-8
IWP-O1 ( —— )
Catalog No. M20089 CAS No. 2074607-48-8
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM) effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
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| 5MG | 87 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 267 | In Stock |
|
| 50MG | 413 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIWP-O1
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NoteResearch use only not for human use.
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Brief DescriptionIWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM) effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
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DescriptionIWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM) effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetPorcupine
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RecptorPorcn
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Research Area——
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Indication——
Chemical Information
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CAS Number2074607-48-8
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Formula Weight432.48
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Molecular FormulaC26H20N6O
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mg/mL
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SMILESO=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1
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Chemical Name5-Phenyl-N-(5-phenylpyridin-2-yl)-4-(pyridin-4-yl)-1H-123-triazol-1-acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.You L et al. Development of a triazole class of highly potent Porcn inhibitors. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5891-5895.
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