Cart
sales@molnova.com
ITX-5061
CAS No. 848144-15-0
ITX-5061( ITX5061 )
Catalog No. M16157 CAS No. 848144-15-0
ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels; inhibits SR-BI-dependent uptake of HDL-CE in transfected cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameITX-5061
-
NoteResearch use only, not for human use.
-
Brief DescriptionITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels; inhibits SR-BI-dependent uptake of HDL-CE in transfected cells.
-
DescriptionITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels; inhibits SR-BI-dependent uptake of HDL-CE in transfected cells, decreases the fractional catabolic rate of HDL-CE and reduced its hepatic uptake in mice; inhibits HCVcc and HCVpp infection of primary human hepatocytes and/or human hepatoma cell lines and has minimal effects on HCV RNA replication.HCV Infection Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsITX5061
-
PathwayImmunology/Inflammation
-
TargetScavenger Receptor
-
RecptorScavenger Receptor
-
Research AreaInfection
-
IndicationHCV Infection
Chemical Information
-
CAS Number848144-15-0
-
Formula Weight583.7
-
Molecular FormulaC30H37N3O7S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(C)(C)C1=CC(=C(C(=C1)NS(=O)(=O)C)OC)NC(=O)C(=O)C2=CC=C(C3=CC=CC=C32)OCCN4CCOCC4
-
Chemical NameN-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Masson D, et al. Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2054-60.
2. Zhu H, et al. J Infect Dis. 2012 Feb 15;205(4):656-62.
3. Syder AJ, et al. J Hepatol. 2011 Jan;54(1):48-55.
molnova catalog
related products
-
ITX-5061 hydrochlori...
ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels.
-
ITX-5061
ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels; inhibits SR-BI-dependent uptake of HDL-CE in transfected cells.
