IMT1B
CAS No. 2304621-06-3
IMT1B ( 3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-; LDC203974 )
Catalog No. M24045 CAS No. 2304621-06-3
IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 295 | In Stock |
|
10MG | 507 | In Stock |
|
25MG | 801 | In Stock |
|
50MG | 1107 | In Stock |
|
100MG | 1503 | In Stock |
|
500MG | 3015 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameIMT1B
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NoteResearch use only, not for human use.
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Brief DescriptionIMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
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DescriptionIMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
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Synonyms3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-; LDC203974
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PathwayOthers
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TargetOther Targets
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RecptorPOLRMT
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Research Area——
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Indication——
Chemical Information
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CAS Number2304621-06-3
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Formula Weight473.9
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Molecular FormulaC24H21ClFNO6
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL?(527.56 mM;?Need ultrasonic)
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SMILESC[C@H](C(=O)N1CCC[C@@H](C1)C(=O)O)OC2=CC3=C(C=C2)C(=CC(=O)O3)C4=C(C=C(C=C4)F)Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nina A Bonekamp, et al. Small-molecule inhibitors of human mitochondrial DNA transcription. Nature. 2020 Dec;588(7839):712-716.
molnova catalog
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