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IMM-01
CAS No. 218795-74-5
IMM-01 ( —— )
Catalog No. M27816 CAS No. 218795-74-5
IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 218 | Get Quote |
|
| 10MG | 309 | Get Quote |
|
| 25MG | 518 | Get Quote |
|
| 50MG | 741 | Get Quote |
|
| 100MG | 1017 | Get Quote |
|
| 500MG | 2052 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIMM-01
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NoteResearch use only, not for human use.
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Brief DescriptionIMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division.
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DescriptionIMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorCYP3A4;Calcium Channel;P-gp
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Research Area——
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Indication——
Chemical Information
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CAS Number218795-74-5
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Formula Weight267.4
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Molecular FormulaC12H17N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)(C)NC(=S)N\N=C\c1ccc(O)cc1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kubo Y, et al. Blood-to-Retina Transport of Fluorescence-Labeled Verapamil at the Blood-Retinal Barrier. Pharm Res. 2018 Mar 12;35(5):93.
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