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IMAB027

CAS No. 1650599-68-0

IMAB027( —— )

Catalog No. M37166 CAS No. 1650599-68-0

IMAB027 (ASP1650) is a specific monoclonal antibody targeting CLDN6 (Claudin 6), a membrane protein of tight junctions aberrantly overexpressed in multiple human cancers, notably ovarian cancers.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    IMAB027
  • Note
    Research use only, not for human use.
  • Brief Description
    IMAB027 (ASP1650) is a specific monoclonal antibody targeting CLDN6 (Claudin 6), a membrane protein of tight junctions aberrantly overexpressed in multiple human cancers, notably ovarian cancers.
  • Description
    IMAB027 (ASP1650) is a specific anti-CLDN6 mAb, while CLDN6 (Claudin 6) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6+ ovarian and testicular cancer cell lines.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1650599-68-0
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Türeci ?, t al. The anti-claudin 6 antibody, IMAB027, induces antibody-dependent cellular and complement-dependent cytotoxicity in claudin 6-expressing cancer cells[J]. Cancer Research, 2018, 78(13_Supplement): 882-882.
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