Cart
sales@molnova.com
IIIC3
CAS No. 524-26-5
IIIC3( Gallocyanine | Dickkopf inhibitor IIIC3 )
Catalog No. M14853 CAS No. 524-26-5
IIIC3 (Gallocyanine;Dickkopf inhibitor IIIC3) is a small-molecule inhibitor of Wnt antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameIIIC3
-
NoteResearch use only, not for human use.
-
Brief DescriptionIIIC3 (Gallocyanine;Dickkopf inhibitor IIIC3) is a small-molecule inhibitor of Wnt antagonist.
-
DescriptionIIIC3 (Gallocyanine;Dickkopf inhibitor IIIC3) is a small-molecule inhibitor of Wnt antagonist Dickkopf with EC50 of 5 uM for reversing DKK1 CM-mediated Wnt inhibition; inhibits the binding of DKK1-alkaline phosphatase (AP) to HEK293 cells expressing the wild-type LRP5 or LRP5 mutant with IC50 of 3 uM; reduces basal blood-glucose concentrations and improves glucose tolerance in mice.
-
In Vitro——
-
In Vivo——
-
SynonymsGallocyanine | Dickkopf inhibitor IIIC3
-
PathwayWnt/Notch/Hedgehog
-
TargetDkk-1
-
RecptorDkk-1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number524-26-5
-
Formula Weight300.27
-
Molecular FormulaC15H12N2O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN(C)C1=CC2=C(C=C1)NC3=C(O2)C(=O)C(=O)C=C3C(=O)O
-
Chemical Name7-(dimethylamino)-4-hydroxy-3-oxo-3H-phenoxazine-1-carboxylic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Li X, et al. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11402-7.
molnova catalog
related products
-
WAY-262611
WAY-262611 (WAY262611) is a potent, orally active and Wnt/β-catenin pathway agonist with EC50 of 0.63 nM.
-
IIIC3
IIIC3 (Gallocyanine;Dickkopf inhibitor IIIC3) is a small-molecule inhibitor of Wnt antagonist.
