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ID-8

CAS No. 147591-46-6

ID-8 ( ID-8; ID 8; ID8 )

Catalog No. M18041 CAS No. 147591-46-6

ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.

Purity : 98%

COA

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Size	Price / USD	Stock	Quantity
5MG	37	In Stock
10MG	51	In Stock
25MG	93	In Stock
50MG	149	In Stock
100MG	266	In Stock
200MG	346	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ID-8
Note

Research use only, not for human use.
Brief Description

ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.
Description

ID-8 is a DYRK inhibitor. ID-8 could support Wnt-induced human embryonic stem cell proliferation and survival without differentiation. Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) is the target of the small molecule ID-8. Its role in human pluripotent cell renewal was confirmed by DYRK knockdown in human embryonic stem cells.
Synonyms

ID-8; ID 8; ID8
Pathway

Others
Target

Other Targets
Recptor

DYRK
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

147591-46-6
Formula Weight

298.29
Molecular Formula

C16H14N2O4
Purity

98%
Solubility

DMSO : ≥ 47 mg/mL; 157.56 mM
SMILES

COc1ccc(cc1)n1c(C)c(c2c1cc(O)cc2)[N+](=O)[O-]
Chemical Name

1-(4-methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Miyabayashi T, et al. Biosci Biotechnol Biochem. 2008 , 72(5), 1242-1248.

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