
IC-9564
CAS No. 174847-98-4
IC-9564( IC9564 | AIDS033640 )
Catalog No. M12649 CAS No. 174847-98-4
IC-9564 (AIDS033640) is a betulinic acid derivative and potent HIV entry inhibitor.
Purity : >98% (HPLC)






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Biological Information
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Product NameIC-9564
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NoteResearch use only, not for human use.
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Brief DescriptionIC-9564 (AIDS033640) is a betulinic acid derivative and potent HIV entry inhibitor.
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DescriptionIC-9564 (AIDS033640) is a betulinic acid derivative and potent HIV entry inhibitor that blocks HIV-1 envelope-mediated membrane fusion with IC90 of 0.22 uM for NL4-3 strain; also has IC90s of >5, 2.65, and 1.84 uM for DH012, QZ4734, and HIV-1 89.6, respectively; HIV-1 gp120 plays a key role in the anti-HIV-1 activity of IC9564.
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In Vitro——
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In Vivo——
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SynonymsIC9564 | AIDS033640
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number174847-98-4
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Formula Weight755.138
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Molecular FormulaC46H78N2O6
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)CC(C(CC(=O)O)O)NC(=O)CCCCCCCNC(=O)C12CCC(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C(=C)C
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Chemical Name(3R,4S)-3-Hydroxy-4-[[8-[[(3β)-3-hydroxy-28-oxolup-20(29)-en-28-yl]amino]-1-oxooctyl]amino]-6-methylheptanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Holz-Smith SL, et al. Antimicrob Agents Chemother. 2001 Jan;45(1):60-6.
2. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.
3. Sun IC, et al. J Med Chem. 2002 Sep 12;45(19):4271-5.
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