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Humantenmine

CAS No. 82354-38-9

Humantenmine( —— )

Catalog No. M19144 CAS No. 82354-38-9

Humantenmine and koumine may inhibit several CYP450 enzyme activities.

Purity : >98% (HPLC)

COA

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HNMR

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Biological Information

Product Name

Humantenmine
Note

Research use only, not for human use.
Brief Description

Humantenmine and koumine may inhibit several CYP450 enzyme activities.
Description

Humantenmine is a toxic compound isolated from Gelsemium elegans Benth. Humantenmine and koumine may inhibit several CYP450 enzyme activities.
In Vitro

Humantenmine (HMT) decreases the 14-day survival rate of the mice to 17% after they are intragastrically treated with HMT, along with hepatic injury and increasing alanine aminotransferase (ALT)/aspartate aminotransferase (AST) levels. CYP3A4/5 mediates the metabolism and detoxification of HMT.
In Vivo

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Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Beta Amyloid
Recptor

CYP450
Research Area

Others-Field
Indication

——

Chemical Information

CAS Number

82354-38-9
Formula Weight

326.39
Molecular Formula

C19H22N2O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (306.38 mM)
SMILES

CCC1=NC2CC3(C4CC1C2CO4)C5=CC=CC=C5N(C3=O)OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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