Helichrysetin

Research use only, not for human use.

Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.

Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives from the methanol extract of Boesenbergia pandurata rhizomes. The known compounds were identified to be panduratin A, hydroxypanduratin A, Helichrysetin, 2',4',6'-trihydroxyhydrochalcone, and uvangoletin . The structures of all compounds were elucidated on the basis of chemical and spectroscopic methods.

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Microbiology/Virology

HIV

HIV

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62014-87-3

286.3

C16H14O5

>98% (HPLC)

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O=C(C1=C(OC)C=C(O)C=C1O)/C=C/C2=CC=C(O)C=C2

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(-20℃)

With Ice Pack

≥ 2 years