Haloperidol ( McN-JR 1625; NSC 170973; NSC 615296; R 1625 )

Catalog No. M14873 CAS No. 52-86-8

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Product Name

Haloperidol
Note

Research use only, not for human use.
Brief Description

Haloperidol has been found to be highlt potent neuroleptic by relieving nervous through the depression of nerve function.
Description

Haloperidol has been found to be highlt potent neuroleptic by relieving nervous through the depression of nerve function. Besides, Haloperidol has shown about 50-fold potency than chiorpromazine, the other antipsychotic drug. Haloperidol has shown beneficial effects in the treatment of delusions and hallucinations. These effects are mainly achieved through blockage of dopamine receptors in the mesocortex and limbic system.
Synonyms

McN-JR 1625; NSC 170973; NSC 615296; R 1625
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT; Dopamine
Research Area

Neurological Disease
Indication

——

CAS Number

52-86-8
Formula Weight

375.87
Molecular Formula

C21H23ClFNO2
Purity

>98%(HPLC)
Solubility

Ethanol: 8 mg/mL (21.28 mM); DMSO: 75 mg/mL (199.54 mM)
SMILES

C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
Chemical Name

4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

1.Cai G, et al. Mol Pharmacol. 1999 Nov;56(5):989-96.

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