HS-10296 ( —— )

Catalog No. M20205 CAS No. 1899921-05-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

HS-10296
Note

Research use only not for human use.
Brief Description

Hs-10296 is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M which has only limited activity against wild-type EGFR.
Description

Hs-10296 is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M which has only limited activity against wild-type EGFR.
Synonyms

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Pathway

Angiogenesis
Target

EGFR
Recptor

EGFR (E746_A750/T790M)
Research Area

——
Indication

——

CAS Number

1899921-05-1
Formula Weight

525.66
Molecular Formula

C30H35N7O2
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (190.24 mM);Ethanol:6 mg/mL (11.41 mM);Water:Insoluble
SMILES

COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C2CC2)c2ccccc12
Chemical Name

N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide