Genistein
CAS No. 446-72-0
Genistein ( CI-75610; NSC 36586 )
Catalog No. M14528 CAS No. 446-72-0
Genistein(NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
50MG | 34 | In Stock |
|
100MG | 49 | In Stock |
|
500MG | 86 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGenistein
-
NoteResearch use only, not for human use.
-
Brief DescriptionGenistein(NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.
-
DescriptionGenistein(NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.
-
SynonymsCI-75610; NSC 36586
-
PathwayAngiogenesis
-
TargetEGFR
-
RecptorEGFR
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number446-72-0
-
Formula Weight270.24
-
Molecular FormulaC15H10O5
-
Purity>98%(HPLC)
-
SolubilityEthanol: 2 mg/mL (7.4 mM); DMSO: 54 mg/mL (199.82 mM)
-
SMILESO=C1C(C2=CC=C(O)C=C2)=COC3=CC(O)=CC(O)=C13
-
Chemical Name5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Akiyama T, et al. J Biol Chem, 1987, 262(12), 5592-5595.
molnova catalog
related products
-
PF 6274484
PF 6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM.
-
CCF642
CCF642 is a novel PDI-inhibiting compound with antimyeloma activity.
-
AEE-788
A potent, orally bioavailable dual EGFR/VEGFR receptor tyrosine kinase inhibitor with IC50 of 2, 6, 77 and 59 nM for EGFR, ErbB2, KDR and Flt-1, respectively.