HPK1-IN-4
CAS No. 2739844-28-9
HPK1-IN-4( —— )
Catalog No. M35202 CAS No. 2739844-28-9
HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 201 | Get Quote |
|
| 5MG | 312 | Get Quote |
|
| 10MG | 471 | Get Quote |
|
| 25MG | 799 | Get Quote |
|
| 50MG | 1095 | Get Quote |
|
| 100MG | 1467 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHPK1-IN-4
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NoteResearch use only, not for human use.
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Brief DescriptionHPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.
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DescriptionHPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0.061 nM) as preclinical immunoresearch tool compound.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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RecptorMAPK
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Research Area——
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Indication——
Chemical Information
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CAS Number2739844-28-9
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Formula Weight434.49
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Molecular FormulaC23H26N6O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (230.15 mM; ultrasonic and adjust pH to 4 with HCl )
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SMILESCOc1cc2CCN(C)Cc2cc1Nc1ncc(C(N)=O)c(Nc2ccccc2CO)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brandon A Vara, et al. Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. ACS Med Chem Lett. 2021 Mar 19;12(4):653-661.?
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